Far Infrared Therapy and Microcirculation

Unlocking Oxygen, Nutrients, and Healing

One of the most profound and well-documented benefits of far infrared (FIR) therapy is its effect on microvascular circulation — the intricate network of capillaries responsible for nourishing tissues, removing metabolic waste, and facilitating cellular regeneration.

Far infrared radiation extends beyond superficial warming of the skin, initiating complex physiological cascades that fundamentally alter blood flow dynamics throughout the body’s tissues.

Research Overview

  • Focus: microvascular circulation — the intricate network of capillaries responsible for nourishing tissues, removing metabolic waste, and facilitating cellular regeneration. [20]
  • Core concept: Far infrared radiation extends beyond superficial warming of the skin, initiating complex physiological cascades that fundamentally alter blood flow dynamics throughout the body’s tissues. [21]

How to read this page

Scan the summary cards first, then explore the expanded sections for deeper context and supporting research.

Biophysical Properties and Penetration Depth

Far infrared radiation, particularly within the 7–14 micron wavelength range, demonstrates unique biophysical properties that enable it to penetrate 3–5 centimeters into subcutaneous tissues. [20]

At this wavelength spectrum, FIR energy is efficiently absorbed by water molecules and organic compounds within tissues, initiating both thermal and non-thermal biological responses. [20]

Far Infrared Energy Penetrates Deeply Into Skin Tissue
Illustration of Far Infrared Energy Penetrating Deeply Into Skin Tissue.

Key sections at a glance

Biophysical Properties and Penetration Depth

Biophysical Properties of Far Infrared Radiation

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Far infrared radiation, particularly within the 7–14 micron wavelength range, demonstrates unique biophysical properties that enable it to penetrate 3–5 centimeters into subcutaneous tissues (Vatansever and Hamblin). [20] At this wavelength spectrum, FIR energy is efficiently absorbed by water molecules and organic compounds within tissues, initiating both thermal and non-thermal biological responses. [20]

Unlike conventional heating methods that primarily warm the skin surface, FIR’s deep tissue penetration directly affects:

  • Subcutaneous microvascular networks
  • Muscular tissue beds
  • Synovial structures around joints
  • Fascial planes and connective tissues

This depth of influence explains why FIR produces circulatory effects that endure long after therapy sessions end, with studies documenting continued enhancement of microvascular function for 24–48 hours post-exposure (Imamura et al.). [6]

Vasodilation and Microvascular Blood Flow Enhancement

Vasodilation and Blood Flow Dynamics

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In brief: FIR exposure promotes vasodilation and increased blood flow through endothelial signaling and nitric oxide-mediated pathways.

When tissues absorb FIR radiation, endothelial cells lining blood vessels respond by upregulating nitric oxide synthase (eNOS) activity. [15] This results in increased production of nitric oxide (NO), a potent vasodilator that relaxes smooth muscle cells within the vascular wall. [15]

FIR-induced vasodilation improves blood flow through several coordinated mechanisms:

  • Relaxation of vascular smooth muscle cells
  • Reduction in peripheral vascular resistance
  • Increased capillary perfusion within treated tissues
  • Improved blood rheology and flow velocity

Multiple clinical investigations using laser Doppler flowmetry have quantified this effect, documenting increases in cutaneous blood flow by 30–60% during FIR exposure, even in subjects at complete rest (Yu et al.). [21]

Importantly, this vasodilatory response occurs without a corresponding increase in heart rate or systemic blood pressure, indicating a localized microvascular effect rather than generalized cardiovascular stress. [21]

Tissue Oxygenation and Cellular Bioenergetics

Improved Oxygen Delivery and Utilization

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In brief: Enhanced microcirculation under FIR exposure increases tissue oxygenation and supports cellular energy production.

As microvascular circulation improves under FIR influence, oxygen delivery to tissues increases dramatically. [4] Near-infrared spectroscopy studies demonstrate that tissue oxygen saturation levels rise by 15–25% during FIR therapy, with maximum effects observed in previously hypoperfused areas (Fujii et al.). [4]

Improved oxygen availability supports several downstream physiological benefits:

  • Enhanced mitochondrial respiration and ATP production
  • Improved cellular metabolism and energy efficiency
  • Accelerated metabolic waste removal
  • Support for tissue repair and regenerative processes

These combined effects contribute to improved functional capacity of tissues and support recovery in areas affected by chronic hypoxia or impaired circulation. [4]

Angiogenesis and Microvascular Remodeling

Angiogenesis and Vascular Adaptation

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In brief: Repeated FIR exposure may promote microvascular remodeling and angiogenesis through growth factor signaling.

With regular application, FIR therapy initiates angiogenesis—the formation of new blood vessels—through upregulation of vascular endothelial growth factor (VEGF) and other angiogenic cytokines. [1]

This microvascular remodeling improves long-term tissue perfusion and enhances resilience against ischemic conditions. [1]

FIR-driven angiogenic effects support:

  • Increased capillary density in chronically underperfused tissues
  • Improved nutrient and oxygen delivery capacity
  • Enhanced tissue repair and regenerative potential
  • Greater metabolic waste clearance through expanded microvascular networks

These structural vascular adaptations help explain why repeated FIR therapy may lead to sustained improvements in circulation over time. [1]

Clinical Manifestations and Therapeutic Applications

Clinical Applications of Enhanced Microcirculation

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In brief: Improved microcirculation may translate into measurable benefits across mobility, recovery, inflammation, and tissue repair contexts.

The enhanced microcirculation induced by FIR therapy directly contributes to decreased tissue stiffness and improved joint mobility through several mechanisms: [14]

  • Increased nutrient delivery to connective tissues
  • Enhanced removal of inflammatory metabolites
  • Reduced local ischemia and hypoxic stress
  • Improved tissue elasticity through better hydration and perfusion

Improved microvascular circulation also supports recovery and repair by increasing oxygen availability and accelerating removal of metabolic waste products. [5]

Clinical and physiological contexts often associated with impaired microcirculation include:

  • Chronic inflammation and inflammatory pain conditions
  • Delayed tissue healing and recovery after injury
  • Peripheral circulation limitations and cold extremities
  • Stiffness and mobility limitations related to poor tissue perfusion

A grounded interpretation

Far infrared therapy exerts profound and well-documented effects on microvascular circulation that extend far beyond simple heating. [20]

Takeaways

  • Far infrared radiation penetrates deeply into tissues, influencing microvascular structures beyond the skin surface.
  • FIR therapy enhances vasodilation and microvascular blood flow through nitric oxide–mediated pathways.
  • Improved circulation supports increased tissue oxygenation and cellular energy production.
  • Repeated FIR exposure may contribute to angiogenesis and long-term improvements in tissue perfusion.
  • Enhanced microcirculation plays a central role in recovery, mobility, and tissue health.

Guidelines

  • Begin with shorter FIR sessions and gradually increase duration as tolerance improves.
  • Maintain adequate hydration to support circulatory and metabolic processes during and after sessions.
  • Use FIR therapy consistently to support sustained microvascular adaptations.
  • Individuals with medical conditions affecting circulation should consult a qualified clinician before initiating therapy.

Conclusion

Far infrared therapy influences microcirculation through a combination of deep tissue penetration, vasodilation, enhanced oxygen delivery, and long-term microvascular remodeling. These effects distinguish FIR from conventional heating methods and position it as a valuable modality for supporting tissue health, recovery, and physiological resilience. [20]

As research continues to clarify the mechanisms and clinical implications of FIR-induced microcirculatory enhancement, this therapy remains an important area of interest for applications involving circulation, mobility, and metabolic support. [18]

References

  1. Akasaki, Yuichi, et al. “Repeated Thermal Therapy Up-Regulates Endothelial Nitric Oxide Synthase and Augments Angiogenesis in a Mouse Model of Hindlimb Ischemia.” Circulation Journal, 2006. View abstract on PubMed (PMID: 16565566)
  2. Beever, Richard. “Far-Infrared Saunas for Treatment of Cardiovascular Risk Factors.” Canadian Family Physician, 2009. View article on journal site
  3. Biro, Sadatoshi, et al. “Clinical Implications of Thermal Therapy in Lifestyle-Related Diseases.” Experimental Biology and Medicine, 2003. View abstract on PubMed (PMID: 14610268)
  4. Fujii, Masafumi, et al. “Effect of Far-Infrared Radiation on the Volume of Peripheral Blood Flow.” Journal of the American Geriatrics Society, 2004. View abstract on PubMed (PMID: 15507054)
  5. Hausswirth, Christophe, et al. “Effects of Whole-Body Far-Infrared Heat on Muscle Damage and Recovery.” Journal of Strength and Conditioning Research, 2011. View abstract on PubMed (PMID: 22076009)
  6. Imamura, Masahiro, et al. “Repeated Thermal Therapy Improves Vascular Endothelial Function.” Journal of the American College of Cardiology, 2001. View abstract on PubMed (PMID: 11583880)
  7. Kihara, Takashi, et al. “Waon Therapy Improves Prognosis of Chronic Heart Failure.” Journal of Cardiology, 2009. View abstract on PubMed (PMID: 19114105)
  8. Ko, Gordon D., and David Berbrayer. “Ceramic-Impregnated Gloves for Raynaud’s Syndrome.” Alternative Medicine Review, 2002. View abstract on PubMed (PMID: 12184512)
  9. Lai, Chien-Hung, et al. “Far-Infrared Radiation for Myofascial Neck Pain.” Journal of Alternative and Complementary Medicine, 2014. View abstract on PubMed (PMID: 29154057)
  10. Lee, Chia-Hua, et al. “Far Infrared–Emitting Ceramic Fabric for Body Pain.” Medicine, 2015. View abstract on PubMed (PMID: 26632712)
  11. Lin, Cheng-Chien, et al. “Far-Infrared Therapy Improves Arteriovenous Fistula Blood Flow.” Journal of the American Society of Nephrology, 2007. View abstract on PubMed (PMID: 17267744)
  1. Masuda, Akinori, et al. “Repeated Thermal Therapy for Chronic Pain.” Psychotherapy and Psychosomatics, 2005. View abstract on PubMed (PMID: 16088266)
  2. Matsushita, Kakushi, et al. “Waon Therapy for Chronic Fatigue Syndrome.” Internal Medicine, 2008. View abstract on PubMed (PMID: 18703857)
  3. Oosterveld, Frans G.J., et al. “Infrared Sauna in Rheumatoid Arthritis and Ankylosing Spondylitis.” Clinical Rheumatology, 2009. View abstract on PubMed (PMID: 18685882)
  4. Park, Jong-Hoon, et al. “Far-Infrared Radiation Increases Nitric Oxide Production.” Biochemical and Biophysical Research Communications, 2013. View abstract on PubMed (PMID: 23727073)
  5. Shin, Jung-Yoon, and Young-Joo Lee. “Far-Infrared Radiation and Erythrocyte Deformability.” Clinical Hemorheology and Microcirculation, 2011. View abstract on PubMed (PMID: 21447911)
  6. Shinsato, Takuro, et al. “Waon Therapy Mobilizes CD34+ Cells.” Journal of Cardiology, 2010. View abstract on PubMed (PMID: 20643241)
  7. Shui, Shanshan, et al. “Far-Infrared Therapy: Systematic Review.” Experimental Biology and Medicine, 2015. View full article on NIH (PMC)
  8. Tei, Chuwa, et al. “Waon Therapy for Chronic Heart Failure.” Circulation Journal, 2009. View abstract on PubMed (PMID: 19443945)
  9. Vatansever, Fatma, and Michael R. Hamblin. “Far Infrared Radiation (FIR): Biological Effects.” Photonics & Lasers in Medicine, 2012. View full article on NIH (PMC)
  10. Yu, Shih-Yu, et al. “Far-Infrared Therapy and Skin Microcirculation.” Photodermatology, Photoimmunology & Photomedicine, 2006. View abstract on PubMed (PMID: 16433634)
  11. Toyokawa, Hideyuki, et al. “Far-Infrared Ray and Wound Healing.” Experimental Biology and Medicine, 2003. View full article on NIH (PMC)
  12. Sobajima, Mitsuo, et al. “Waon Therapy Improves Pulmonary Hypertension.” Journal of Cardiology, 2013. View abstract on PubMed (PMID: 23276604)

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