Scientific Studies

Overview and Mechanistic Studies

• Vatansever, Fatma, and Michael R Hamblin. “Far infrared radiation (FIR): its biological effects and medical applications.” Photonics & Lasers in Medicine, vol. 4 (2012): 255-266. doi:10.1515/plm-2012-0034

• Ishibashi J, et al. “The effects inhibiting the proliferation of cancer cells by far-infrared radiation (FIR) are controlled by the basal expression level of heat shock protein (HSP) 70A.” Med Oncol. 2008;25(2):229-37. doi:10.1007/s12032-007-9020-4

• Ferraresi C, et al. “Low-level laser (light) therapy increases mitochondrial membrane potential and ATP synthesis in C2C12 myotubes with a peak response at 3–6 h.” Photochem Photobiol. 2015;91(2):411–416. doi:10.1111/php.12397

• Begum, Rana et al. “Near-infrared light increases ATP, extends lifespan and improves mobility in aged Drosophila melanogaster.” Biology Letters, vol. 11,3 (2015): 20150073. doi:10.1098/rsbl.2015.0073

• “Do Infrared Saunas Have Any Health Benefits?” Mayo Clinic, Mayo Foundation for Medical Education and Research, 13 Sept. 2024, www.mayoclinic.org/healthy-lifestyle/consumer-health/expert-answers/infrared-sauna/faq-20057954.

• Crinnion, Walter J. “Sauna as a valuable clinical tool for cardiovascular, autoimmune, toxicant-induced and other chronic health problems.” Alternative Medicine Review, vol. 16, no. 3, Sept. 2011, https://go.gale.com/ps/i.do?p=AONE&u=googlescholar&id=GALE%7CA269530998&v=2.1&it=r&sid=AONE&asid=492105ef.

Cancer Therapy Adjuncts

• Prosnitz, L, and E Jones. “Counterpoint: test the value of hyperthermia in patients with carcinoma of the cervix being treated with concurrent chemotherapy and radiation.” Int J Hyperthermia, vol. 18,1 (2002): 13–18. doi:10.1080/02656730110083747

Wound Healing and Tissue Repair

• Lin, Yu-Hsin, and Tzong-Shiun Li. “The Application of Far-Infrared in the Treatment of Wound Healing: A Short Evidence-Based Analysis.” J Evid Based Complementary Altern Med, vol. 22,1 (2017): 186–188. doi:10.1177/2156587215623436

• Lin, Cheng-De, et al. “Far-infrared rays penetrate deeper into mammary tissue and induce a higher skin blood flow in comparison to infrared irradiation.” The Second Asian and Pacific Rim Symposium on Biophotonics, 2004. APBP 2004., Taipei, Taiwan, 2004, pp. 107–108. doi:10.1109/APBP.2004.1412302

Chronic Fatigue and Systemic Wellness

• Masuda, Akinori et al. “The effects of repeated thermal therapy for two patients with chronic fatigue syndrome.” J Psychosom Res, vol. 58,4 (2005): 383–387. doi:10.1016/j.jpsychores.2004.11.005

Inflammatory and Autoimmune Disorders

• Oosterveld, F.G.J., et al. “Infrared sauna in patients with rheumatoid arthritis and ankylosing spondylitis.” Clin Rheumatol 28, 29–34 (2009). https://doi.org/10.1007/s10067-008-0977-y

• Rébé, Cédric, François Ghiringhelli, and Carmen Garrido. “Can the hyperthermia-mediated heat shock factor/heat shock protein 70 pathway dampen the cytokine storm during SARS-CoV-2 infection?” British Journal of Pharmacology, first published 11 Dec. 2020. doi:10.1111/bph.15343

Cardiovascular and Circulatory Health

• Lin, Chih-Ching et al. “Far-infrared therapy: a novel treatment to improve access blood flow and unassisted patency of arteriovenous fistula in hemodialysis patients.” J Am Soc Nephrol, vol. 18,3 (2007): 985–992. doi:10.1681/ASN.2006050534

• Kihara, Takashi et al. “Repeated sauna treatment improves vascular endothelial and cardiac function in patients with chronic heart failure.” J Am Coll Cardiol, vol. 39,5 (2002): 754–759. doi:10.1016/s0735-1097(01)01824-1

Detoxification and Environmental Toxin Elimination

• McAdams, Alexis. “IFD Firefighters Sweat Out Dangerous Toxins to Fight Back Against Growing Cancer Epidemic.” Fox 59, 20 Apr. 2017. [Posted 10:26 PM EDT; Updated 11:15 PM EDT]

Weight Loss

• Eun-Mo, Song, et al. “Effects of Far-Infrared Therapy on Weight Loss in Korean Obese Women.” Journal of Korean Medicine for Obesity Research, The Society of Korean Medicine for Obesity Research, 20 June 2012, koreascience.kr/article/JAKO201225150622267.page.

• Lee, Earric et al. “Effects of regular sauna bathing in conjunction with exercise on cardiovascular function: a multi-arm, randomized controlled trial.” American journal of physiology. Regulatory, integrative and comparative physiology vol. 323,3 (2022): R289-R299. doi:10.1152/ajpregu.00076.2022

Mental Health and Mood Regulation

• Yatsuzuka, Miki, et al. “Psychological Characteristics after Far-infrared Hyperthermia Evaluated Using the Profile of Mood State (POMS).” Faculty of Medicine, Toyama Medical and Pharmaceutical University, Toyama, Japan.

Trials and Proof of Concept

• Broeder, Craig E., FACSM. “Relax Saunas: Proof of Concept – Initial Trial Summary.” Exercising Nutritionally, LLC, Prepared 28 Mar. 2022.